Table 4.

Fluid overload and outcome in children receiving continuous RRT

StudyCohort (n)OutcomeP
Goldstein (25)Single center (22)Survivors 16% FO0.03
Nonsurvivors 34% FO
Gillespie (27)Single center (77)%FO >10% with OR for death 3.020.002
Foland (28)Single center (113)3 patients with MODS0.01
Survivors 9% FO
Nonsurvivors 16% FO
1.78 OR for death for each 10% FO increase
Goldstein (29)Multicenter (116)≥2 patients with MODS0.002
Survivors 14% FO
Nonsurvivors 25% FO
<20% FO: 58% survival
>20% FO: 40% survival
Hayes (26)Single center (76)Survivors 7% FO0.001
Nonsurvivors 22% FO
OR for death 6.1 >20% FO
  • FO, fluid overload; MODS, multiorgan dysfunction syndrome; OR, odds ratio.