Table 7.

Renal biopsy findings of hepatitis-negative patients with MPGN and monoclonal gammopathy

PatientPattern of Glomerular InjuryTotal Glomeruli/Globally Sclerosed GlomeruliTubulointerstitial Scarring (%)Immunofluorescence StudiesEMClinical Diagnosis
1MPGN18/110IgM, λDC, SU, Mes.MGUS
2MPGN16/010Negative, C3DC, SU, MesMGUS
3MPGN17/230IgM, κDC, SUMGUS
4MPGN6/120IgM, κDC, SU, MesMGUS
5MPGN6/10IgM, κDC, SU, MesMGUS
6MPGN16/010Negative, C3DC, SU, MesMGUS
7MPGN26/010IgG, λDC, SU, MesMGUS
8MPGN21/18100Global sclerosisDC, SU, MesMGUS
9MPGN8/10IgM, κDC, SU, MesMGUS
10MPGN33/520IgM, κDC, SU, MesMGUS
11MPGN8/010IgG, κDC, SU, MesMGUS
12MPGN19/410IgG, κDC, SU, MesMGUS
13MPGN18/00No glomeruliDC, SU, MesMGUS
14MPGN16/05 to 10IgGDC, SU, MesMGUS
15MPGN13/220IgM, κSU, MesMGUS
16MPGN13/210IgM, κNo glomeruliMGUS
17MPGN15/25IgG, IgM, λDC, SU, SE, MesLGBCL
18MPGN18/210NegativeDC, SUMM
19MPGN10/790IgM, κNDCLL
20MPGN6/115 to 20IgM, κDC, SU, MesLGBCL
21MPGN9/325C3DC, SU, MesCLL
22MPGN4/00NegativeDC, SU, MesMM
23MPGN16/1050IgG, κDC, SU, MesMM
24MPGN5/00IgM, κDC, SU, MesLPL
25MPGN14/550IgGDC, SUMM
26MPGN20/220IgM, κDC, SULGBCL
27MPGN4/010No glomeruliDC, SUMM
28MPGN14/20IgG, κDC, SUMM
  • DC, double contours; Mes, mesangial electron-dense deposits; SE, subepithelial electron-dense deposits; SU, subendothelial electron-dense deposits.