Table 6.

Summary of bone marrow biopsy results of hepatitis-negative MPGN cases showing monoclonal bands on electrophoresis studies

PatientCellularityPlasma Cell %PC Light ChainLymphoid InfiltrateLymphocyte Light Chain% Lymphoid InvolvementFlow CytometryClinical Diagnosis
1Increased5κNoNoNegativeMGUS
2Normal<5NDNoND<5NDMGUS
3Normal<5NoNoNoNegativeMGUS
4Decreased8NDNoNDNDMGUS
5Normal<5NDNoκ<5NoMGUS
6Increased5NoNoNoNegativeMGUS
7Normal5λNoNDPCMGUS
8Normal5 to 10λNoNoPCMGUS
9Normal<5κYesλ<5PC, LyMGUS
10Decreased<5NoNoNoNegativeMGUS
11Normal<5NoNoNoNegativeMGUS
12Normal5 to 10κNoNoPCMGUS
13Decreased<5NoNoNoNegativeMGUS
14Decreased5 to 10κNoNoPCMGUS
15Decreased<5NoNoNoNegativeMGUS
16Normal<5NoYesκ30LyMGUS
17Normal<5NoYesλ<5LyLGBCL
18Normal15λNoNDPCMM
19Increased<5NoYesκ30LyCLL
20Increased<5NoYesκ20 to 30LyLGBCL
21Increased<5NoYesκ80LyCLL
22Increased12κNoNoPCMM
23Normal10 to 15κNoNDPCMM
24Normal5κYesκ10PC, LyLPL
25Normal20κNoNoPCMM
26Increased<5NoYesκ5 to 10LyLGBCL
27Normal10λNoNoPCMM
28Increased70 to 80κNoNoPCMM
  • CMPD, chronic myeloproliferative disease; Ly, lymphocytes; ND, not done; PC, plasma cell.