Clinical features of hepatitis-negative patients with MPGN and lymphoproliferative disorders or MM
Patient | Age (years) | Gender | BP (mmHg) | SCr (mg/dl) | Proteinuria (g/24 h) | CrCl (ml/min) | SPEP | SIFE | UPEP | UIFE | Cryo | κ FLC, λ FLC, κ/λ Ratio | Clinical Diagnosis |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
17 | 68 | F | 174/79 | 1.5 | 4.5 | 44 | Hypo | IgG and IgM λ | Negative | IgG λ | Negative | 1.86, 1.81, 1.03 | LGBCL |
18 | 43 | F | 155/93 | 2.2 | 4.8 | 36 | Abnormal fraction | IgG λ | M spike | λ | ND | 0.670, 63.400, 0.010 | MM |
19 | 70 | M | – | 5.6 | 5.3 | 6 | Negative | IgM κ and IgM λ | Negative | Negative | Negative | ND | CLL |
20 | 82 | M | 156/88 | 1.9 | 10.2 | 44 | Abnormal fraction | IgM κ and IgG λ | ND | IgG λ | Negative | 4.53, 2.56, 1.77 | LGBCL |
21 | 75 | M | 150/60 | 2.4 | 4.084 | 25 | Abnormal fraction | IgM and IgG κ | ND | IgG κ | Type I (IgG κ) | 5.21, 1.73, 3.01 | CLL |
22 | 33 | F | 112/80 | 1.7 | 0.311 | 35 | Negative | Negative | Negative | IgG κ | ND | 45.30, 2.64, 17.20 | MM |
23 | 63 | M | 111/67 | 1.3 | 5.216 | 32 | M spike | Monoclonal IgG κ | M spike | IgG κ | ND | 12.80, 17.40, 0.74 | MM |
24 | 71 | M | 130/70 | 1.5 | 1.815 | 40 | M spike | Monoclonal IgM κ | Negative | κ | Negative | 16.70, 0.89, 18.80 | LPL |
25 | 54 | M | 130/78 | 1.5 | 8.2 | 52 | M spike | Monoclonal IgG κ | M spike | IgG κ | Negative | 157.00, 1.61, 97.50 | MM |
26 | 77 | F | 155/81 | 1.3 | 8.3 | 42 | Hypo | Monoclonal IgM κ | Negative | IgM κ | Type II | ND | LGBCL |
27 | 60 | M | 145/87 | 2.3 | 2.9 | 31 | M spike | Monoclonal IgG λ | Negative | IgG λ | Negative | 3.17, 5.55, 0.57 | MM |
28 | 61 | F | 121/59 | 2.2 | 3.1 | 24 | Hypo | Monoclonal IgG κ | Negative | Negative | Negative | 1.46, 1.10, 1.33 | MM |
CrCl, creatinine clearance; Cryo, cryoglobulins; FLC, free light chains (reference range κ FLC 0.33 to 1.94 mg/dl, λ FLC 0.57 to 2.63 mg/dl, κ/λ ratio 0.26 to 1.65); Hypo, hypogammaglobulinemia; ND, not done, SCr, serum creatinine.