Beneficial effects of EGDT of severe sepsis and septic shock (7 to 72 hours)a
| Standard | Early Goal | P Value | |
|---|---|---|---|
| In-hospital mortality (%) | 46.5 | 30.5 | <0.009 |
| SCVO2 (%) | 65.3 | 70.4 | <0.02 |
| Lactate (mmol/L) | 3.9 | 3.0 | <0.02 |
| PH | 7.36 | 7.4 | <0.02 |
| Mechanical ventilation (%) | 16.8 | 2.6 | <0.001 |
| Fibrin split product (μg/dl) | 62 | 39 | <0.001 |
↵a Data from reference 2.