Table 3.

Associations among baseline risk factors; serial BP values; and changes in LVMI, LVVI, and fractional shortening between first and last echocardiograms

ParameterIncrement or Reference CategoryUnadjusted (OR [95% CI])PAdjusted, Model 1 (OR [95% CI])PAdjusted, Model 2 (OR [95% CI])P
ΔLVMI >0 g/m2 (326/524)
    female genderMale0.69 (0.48 to 0.99)0.05
    “other” renal diseaseGN1.58 (1.01 to 2.47)0.041.69 (1.06 to 2.68)0.031.72 (1.02 to 2.90)0.04
    months on dialysis1.5 months1.06 (1.01 to 1.12)0.031.06 (1.00 to 1.12)0.05
    serial SBP4.1 mmHg1.07 (1.02 to 1.13)<0.011.06 (1.01 to 1.12)0.021.09 (1.03 to 1.15)<0.01
    BNP76 ng/ml0.98 (0.96 to 1.00)0.010.98 (0.96 to 1.00)0.010.98 (0.96 to 1.00)0.01
ΔLVMI >26.8 g/m2 (174/524)a
    age6.3 years1.09 (1.01 to 1.17)0.031.09 (1.01 to 1.18)0.021.09 (1.01 to 1.18)0.02
    serial SBP4.1 mmHg1.08 (1.02 to 1.13)<0.011.06 (1.01 to 1.12)0.021.06 (1.01 to 1.12)0.02
New LVH (122/300)
    female genderMale1.84 (1.11 to 3.03)0.021.84 (1.11 to 3.05)0.022.23 (1.30 to 3.84)<0.01
    serial SBP4.1 mmHg1.08 (1.01 to 1.16)0.031.08 (1.01 to 1.16)0.03
ΔLVVI >0 ml/m2 (258/524)
    female genderMale0.65 (0.45 to 0.94)0.02
    diabetesGN0.56 (0.33 to 0.95)0.030.52 (0.30 to 0.91)0.020.51 (0.29 to 0.90)0.02
    months on dialysis1.5 months1.07 (1.01 to 1.12)0.011.07 (1.01 to 1.12)0.021.06 (1.01 to 1.12)0.02
    high target HbLow0.70 (0.50 to 0.99)0.050.68 (0.48 to 0.98)0.04
ΔLVVI >9.6 ml/m2 (177/524)a
    urea reduction ratio6.3%0.90 (0.81 to 1.00)0.050.90 (0.81 to 1.00)0.05
ΔFS <0 (203/522)
    age6.3 years1.14 (1.06 to 1.23)<0.011.14 (1.06 to 1.22)<0.011.12 (1.04 to 1.21)<0.01
    catheterFistula1.82 (1.03 to 3.21)0.04
    BMI1.5 kg/m21.08 (1.03 to 1.13)<0.011.06 (1.01 to 1.11)0.021.06 (1.01 to 1.11)0.02
    urea reduction ratio6.3%0.88 (0.79 to 0.98)0.02
ΔFS <−1.8% (174/522)b
    age6.3 years1.12 (1.05 to 1.20)<0.011.12 (1.04 to 1.20)<0.011.11 (1.04 to 1.20)<0.01
    BMI1.5 kg/m21.05 (1.00 to 1.10)0.04
    albumin0.10.94 (0.89 to 0.99)0.03
    urea reduction ratio6.3%0.88 (0.79 to 0.98)0.020.88 (0.79 to 0.98)0.020.88 (0.79 to 0.98)0.02
  • Parameter estimates for continuous variables were computed for intervals equal to one half the interquartile range. All of the variables shown in Table 1 were considered; only those with the P < 0.05 are shown. Model 1 adjusted for age and gender; model 2 adjusted for age, gender, and variables with P < 0.05 in model 1. Δ, last value minus first value; GN, glomerulonephritis; FS, fractional shortening; OR, odds ratio.

  • a Highest tertile of change between first and last echocardiograms.

  • b Lowest tertile of change between first and last echocardiograms.