Table 1.

Baseline characteristics and serial BP values

CharacteristicValue
Demographic characteristics (n = 596)
    age (years; median [25th to 75th percentiles])51.5 (39 to 62)
    female (%)39.6
    nonwhite race (%)10.6
Clinical characteristics (n = 596)
    renal disease (%)
    glomerulonephritis (%)28.7
    diabetes (%)17.8
    hypertension (%)8.1
    polycystic kidney disease (%)9.1
    other/unknown (%)36.4
    dialysis duration (months; median [25th to 75th percentiles])9 (6 to 14)
    dialysis access (%)
        fistula84.2
        graft5.5
        catheter10.2
    assigned to high Hb target (%)49.7
    epoetin dosage (U/wk; median [25th to 75th percentiles])6000 (4000 to 8000)
    BMI (kg/m2; median [25th to 75th percentiles])25.5 (22.6 to 29.3)
    SBP (mmHg; median [25th to 75th percentiles])143 (130 to 155)
    DBP (mmHg; median [25th to 75th percentiles])80 (72 to 90)
    interdialytic weight gain (kg; median [25th to 75th percentiles])a2.1 (1.4 to 2.8)
Routine laboratory tests (median [25th to 75th percentiles]; n = 596)
    Hb (g/dl)11.1 (10.3 to 1.8)
    serum albumin (g/L)4.0 (3.8 to 4.1)
    urea reduction ratio (%)b67.0 (59.9 to 72.5)
Specialized laboratory tests (median [25th to 75th percentiles]; n = 487)
    BNP (mg/ml)288 (135 to 647)
    Troponin T (ng/ml)0.02 (0.01 to 0.05)
    C-reactive protein (mg/L)3.47 (1.47 to 7.75)
    IL-6 (pg/ml)4.38 (2.67 to 8.68)
Echocardiographic parameters (median [25th to 75th percentiles]; n = 596)
    LVMI (g/m2)108 (91 to 135)
    LVVI (ml/m2)70 (53 to 84)
    fractional shortening (%)36 (30 to 41)
Serial BP, first to last echocardiogram (median [25th to 75th percentiles]; n = 524)
    SBP (mmHg)140 (132 to 150)
    DBP (mmHg)80 (74 to 86)
  • a Interdialytic weight gain was missing for 13 patients.

  • b Urea reduction ratio was missing for 43 patients.