Table 3.

Histologic features in biopsies from patients with recurrent iMN

PatientDays after TxIndication for BiopsyUPGDLight MicroscopyIFElectron MicroscopyStage
GlomeruliSpikesDepositsF/TA (%)IgGC3IgAIgMC1qSEDDFPF/FPE (%)TRI
16ProtocolaNegNo17NoYes02+1+0001+4001
213GD<0.5Yes3NoNo01 to 2+00001+9501
311GD2+Yes18NoNo02 to 3+0 to 1+000NDNDND1
419GD3+Yes13NoYes151+1+01+0NDNDND1
519GD380 mgYes17NoNo<52+0000NDNDND1
653GD2+Yes24NoNo<53+0+000NDNDND1
7104GDTraceYes5YesNo502 to 3+0 to 1+0003+9001
8414GD/NRPNRPYes12YesYes153+1+000NDNDND2
9599GD/NRPNRPYes12NoYes<53+1+0001+10001
10674NRPNRPNo5YesYesND3+1+0002+10002
11721GD/NRPNRPYes9YesYes203+1 to 2+000NDNDND2
12963NRPNRPNo35YesNo152 to 3+1+0001 to 2+9502
13b1203NRPNRPNo14YesYes150000 to 1+013002
143545NRPNRPNo14NoYes153+1+0001+9002
155497NRPNRPNo12YesYes102 to 3+1+0001Mild02
  • FPF/FPE, foot process fusion/foot process effacement; F/TA, fibrosis and tubular atrophy; GD, graft dysfunction; ND, not done; NRP, nephrotic-range proteinuria; SEDD, subepithelial dense deposits; TRI, tubuloreticular inclusions; Tx, transplantation; UP, urinary protein.

  • a Patient underwent ABO-incompatible renal transplantation.

  • b IF negative probably because of the segmental nature of the MN in this patient, which was also noted in his native biopsy.