Table 3.

HRs and 95% CIs of 5-year mortality according to tertiles of dietary phosphorus intake in 224 MHD patients (October 2001 to January 2007)

Death HR (95% CI) [P]Dietary Phosphorus Intake TertilesP for trend
Tertile 1 (n = 74)Tertile 2 (n = 74)Tertile 3 (n = 76)
Unadjusted1.001.49 (0.84, 2.64) [0.16]1.84 (1.07, 3.19) [0.02]0.02
Case-mixa adjusted1.001.66 (0.91, 3.02) [0.09]1.89 (1.04, 3.43) [0.03]0.02
Case-mix + dietb + serum phosphorus1.001.96 (1.02, 3.74) [0.04]2.59 (1.10, 6.08) [0.02]0.03
Case-mix + diet + MICSc + inflammationd adjusted1.001.88 (0.89, 3.95) [0.09]2.37 (1.01, 6.32) [0.04]0.04
  • a Case-mix variables include age, gender, race/ethnicity, diabetes, dialysis vintage, insurance (Medicare), marital status, modified Charlson comorbidity score, dialysis dose (Kt/V), intake of sevelamer HCl or calcium-based binders, and kidney residual urine.

  • b Diet includes calorie, protein, and potassium intakes.

  • c MICS variables include albumin, erythropoietin dose, creatinine, hemoglobin, serum phosphorus, nPCR, bicarbonate, calcium, ferritin, white blood cell, lymphocyte percent, body mass index, and vitamin D dose.

  • d Inflammatory markers include CRP, IL-6, and TNF-α.