Table 6.

Adjusted prevalence of CKD, by CKD-EPI equation estimation of GFR, among those with prediabetes versus no diabetes, by selected characteristics, NHANES 1999 through 2006

Characteristic% with Stages 1 through 4 CKD (95% CI)
PrediabetesNo DiabetesPa
Overall13.1 (11.5 to 14.9)10.6 (9.3 to 12.1)0.012
Age (years)
    20 to 598.7 (7.0 to 10.9)5.6 (4.7 to 6.7)0.001
    ≥6035.1 (32.6 to 37.6)29.4 (26.2 to 32.8)0.052
Gender
    male9.9 (8.4 to 11.7)9.0 (7.5 to 10.7)0.580
    female17.1 (14.0 to 20.1)12.5 (10.5 to 14.7)0.009
Race/ethnicityb
    non-Hispanic white18.9 (10.8 to 15.4)10.6 (9.0 to 12.4)0.042
    non-Hispanic black17.3 (13.4 to 22.1)13.1 (10.8 to 15.9)0.130
    Mexican American12.5 (9.5 to 16.2)8.1 (6.0 to 10.7)0.056
BMI (kg/m2)
    <3011.3 (9.6 to 13.4)9.5 (8.0 to 11.1)0.073
    ≥3014.7 (12.0 to 17.9)12.0 (10.0 to 14.9)0.194
Self-reported hypertension
    yes26.7 (22.7 to 31.0)22.9 (19.7 to 26.5)0.217
    no8.3 (6.7 to 10.2)6.9 (5.8 to 8.4)0.100
  • CKD defined by CKD-EPI equation–calculated eGFR <60 ml/min per 1.73 m2 or single micro/macroalbuminuria measurement; prediabetes, FPG ≥100 and <126 mg/dl and no self-report of diabetes; no diabetes, FPG <100 mg/dl and no self-report of diabetes.

  • a Prevalence estimates adjusted for age, gender, and race/ethnicity, excluding variables being examined (e.g., age-stratified prevalence adjusted for gender and race/ethnicity only). Models that produced prevalence estimates included individuals in all four categories of diabetes status; models that produced P values included only those with prediabetes or no diabetes.

  • b Prevalence for other race/ethnicity not shown because of small sample sizes, but individuals in category are included in all analyses.