Table 5.

Adjusted prevalence of CKD, by MDRD Study equation estimation of GFR, among those with prediabetes versus no diabetes, by selected characteristics, NHANES 1999 through 2006

Characteristic% with Stages 1 through 4 CKD (95% CI)
PrediabetesNo DiabetesPa
Overall17.1 (15.9 to 18.5)11.8 (10.5 to 13.3)<0.001
Age (years)
    20 to 5911.7 (10.6 to 12.9)6.3 (5.4 to 7.4)0.001
    ≥6036.9 (34.3 to 39.5)31.5 (28.4 to 34.8)0.164
Gender
    male14.3 (12.9 to 15.8)8.1 (6.9 to 9.6)0.172
    female18.6 (17.0 to 20.4)13.3 (11.5 to 15.4)0.001
Race/ethnicityb
    non-Hispanic white15.8 (14.4 to 17.2)10.7 (9.3 to 12.3)0.005
    non-Hispanic black20.4 (18.3 to 22.7)12.9 (10.9 to 15.3)0.036
    Mexican American14.5 (12.7 to 16.6)7.6 (6.0 to 9.5)0.035
BMI (kg/m2)
    <3014.6 (13.1 to 16.3)9.7 (8.5 to 11.2)0.017
    ≥3017.9 (15.8 to 20.2)11.5 (9.6 to 13.8)0.008
Self-reported hypertension
    yes29.5 (27.1 to 31.9)21.6 (18.7 to 24.8)0.011
    no10.7 (9.3 to 12.4)7.1 (6.0 to 8.3)0.121
  • CKD defined by MDRD Study equation–calculated eGFR <60 ml/min per 1.73 m2 or single micro/macroalbuminuria measurement; prediabetes, FPG ≥100 and <126 mg/dl and no self-report of diabetes; no diabetes, FPG <100 mg/dl and no self-report of diabetes. BMI, body mass index; CI, confidence interval.

  • a Prevalence estimates adjusted for age, gender, and race/ethnicity, excluding variables being examined (e.g., age-stratified prevalence adjusted for gender and race/ethnicity only). Models that produced prevalence estimates included individuals in all four categories of diabetes status; models that produced P values included only those with prediabetes or no diabetes.

  • b Prevalence for other race/ethnicity not shown because of small sample sizes, but individuals in category are included in all analyses.