Table 1.

Characteristics of patients with CKD by anemia treatment at baseline, 2002 through 2007

CharacteristicAnemia Treatment Group
No Treatment (n = 35,364 [36.2%])Iron Only (n = 35,420 [36.3%])ESA Only (n = 16,439 [16.8%])ESA+Iron (n = 10,413 [10.7%])
Demographics (n [%])
    age (years)
        <45263 (0.7)312 (0.9)367 (2.2)169 (2.0)
        45–648396 (23.7)8111 (22.9)5509 (33.5)3448 (33.1)
        65–7410,501 (29.7)9586 (27.1)4558 (27.7)2937 (28.2)
        ≥7516,204 (45.8)17,411 (49.2)6005 (36.5)3859 (37.1)
    gender
        male34,415 (97.3)34,191 (96.5)16,052 (97.6)10,170 (97.7)
        female949 (2.7)1229 (3.5)387 (2.4)243 (2.3)
    race
        white28,855 (81.6)27,686 (78.2)12,375 (75.3)7784 (74.8)
        black6240 (17.6)7414 (20.9)3861 (23.5)2512 (24.1)
        other269 (0.8)320 (0.9)203 (1.2)117 (1.0)
CKD and anemia characteristics
    Hb (median [IQR])8.8 (7.9 to 9.8)10.1 (9.3 to 10.6)10.7 (9.5 to 12.1)10.9 (9.7 to 12.4)
    eGFR (n [%])
        45–6012,732 (36.0)13,822 (39.0)4149 (25.2)2710 (26.0)
        30–4510,287 (29.1)11,569 (32.7)4127 (25.1)2634 (25.3)
        15–306226 (17.6)7534 (21.3)4988 (30.3)3220 (30.9)
        <151973 (5.6)2221 (6.3)2970 (18.1)1753 (16.8)
    CKD diagnosis by ICD-9 (n [%])8254 (23.3)12,153 (34.3)8871 (54.0)6062 (58.2)
    anemia diagnosis by ICD-9 (n [%])12,544 (35.5)21,566 (60.9)9347 (56.9)6875 (66.0)
    nephrologist (n [%])3161 (14.7)5111 (19.1)4538 (37.7)3235 (40.6)
    hematologist (n [%])2405 (11.2)2811 (10.5)2599 (21.6)1735 (21.8)
Other comorbidities and patient characteristics (n [%])
    diabetes10,364 (29.3)17,446 (49.3)7151 (43.5)5170 (49.6)
    hypertension10,003 (28.3)13,815 (39.0)5387 (32.8)4086 (39.2)
    CAD10,260 (29.0)13,499 (38.1)5084 (30.9)3912 (37.6)
    atrial fibrillation4141 (11.7)5704 (16.1)1434 (8.7)1226 (11.8)
    CHF7428 (21.0)10,863 (30.7)3765 (22.9)3208 (30.8)
    COPD6363 (18.0)8792 (24.8)2667 (16.2)2178 (20.9)
    hypercholesterolemia9559 (27.0)15,265 (43.1)6681 (40.6)4757 (45.7)
    history of hospitalizations in last 12 months32,843 (92.9)17,395 (49.1)5404 (32.9)3636 (34.9)
  • CAD, coronary artery disease; CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; IQR, interquartile range.