Table 3.

Performance of FPG in the screening for a diabetic 2h-PG (≥200 mg/dl)

FPG (mg/dl [mmol/L])Diabetes Identified (n = 56)OGTTs Required (%)Sensitivity (95% CI)Specificity (95% CI)
≥92 (5.1)a49463 (53)0.88 (0.76 to 0.94)0.49 (0.45 to 0.52)
≥94 (5.2)43402 (46)0.77 (0.64 to 0.86)0.56 (0.53 to 0.59)
≥95 (5.3)40349 (40)0.71 (0.59 to 0.82)0.63 (0.59 to 0.66)
≥97 (5.4)b37297 (34)0.66 (0.53 to 0.77)0.68 (0.65 to 0.71)
≥99 (5.5)31244 (28)0.55 (0.42 to 0.68)0.74 (0.71 to 0.77)
≥100 (5.6)27210 (24)0.48 (0.36 to 0.61)0.78 (0.74 to 0.80)
≥103 (5.7)24173 (20)0.43 (0.31 to 0.56)0.82 (0.79 to 0.84)
≥105 (5.8)22137 (16)0.39 (0.28 to 0.52)0.86 (0.83 to 0.88)
≥106 (5.9)17105 (12)0.30 (0.20 to 0.43)0.89 (0.87 to 0.91)
≥108 (6.0)1483 (10)0.25 (0.16 to 0.37)0.92 (0.89 to 0.93)
≥110 (6.1)1263 (7)0.21 (0.13 to 0.34)0.94 (0.92 to 0.95)
  • ROC analyses in patients with FPG <126 mg/dl (n = 873 of 889 patients). The ROC curve AUC value is 0.734 (95% CI 0.674 to 0.795).

  • a Youden index; the FPG value with the largest vertical distance between the ROC curve and the reference line.

  • b FPG value for which the ROC curve is closest to the upper left hand corner of the ROC curve.