Table 2.

Demographic, clinical, and laboratory results at referral for KTx

ParameterNormalIFGIGTDiabetesOverallPa
n48710023072889
Age (years; mean ± SD)50.7 (15.0)g,h,i57.3 (13.6)j57.4 (12.8)j59.2 (13.2)j53.9 (14.6)<0.001
Female gender (n [%])187 (38)g,h,i20 (20)j72 (31)j19 (26)j298 (34)0.001
Nonwhite ethnicity (n [%])34 (7)4 (4)6 (3)6 (8)50 (6)0.285b
BMI (kg/m2; mean ± SD)25.1 (3.9)i25.9 (3.5)25.6 (3.9)26.7 (4.1)j25.4 (3.9)0.003
Hemodialysis (n [%])c160 (33)26 (26)61 (27)29 (41)276 (31)0.056c
Peritoneal dialysis (n [%])c33 (7)9 (9)19 (8)4 (6)65 (7)0.753c
Not in dialysis (n [%])c290 (60)64 (65)149 (65)37 (53)540 (62)0.235c
Time on waiting list (weeks; median [IQR])d54 (30 to 94)60 (36 to 95)64 (38 to 102)70 (42 to 98)58 (35 to 96)0.006
Time on dialysis (weeks; median [IQR])0 (0 to 15)0 (0 to 12)0 (0 to 11)0 (0 to 17)0 (0 to 14)0.710
Prednisolone use (n [%])e42 (13)3 (5)16 (12)5 (12)66 (12)0.999b
Hemoglobin (g/dl; mean ± SD)12.0 (1.5)12.1 (1.3)11.9 (1.5)11.9 (1.2)12.0 (1.4)0.607
Total cholesterol (mg/dl; mean ± SD)186 (46)186 (39)183 (47)179 (51)183 (47)0.434
Albumin (g/dl; mean ± SD)4.0 (0.5)4.0 (0.5)h3.9 (0.5)g3.9 (0.5)3.9 (0.5)0.054
A1c (%; mean ± SD)f5.4 (0.5)i5.6 (0.5)5.6 (0.5)5.7 (0.6)j5.5 (0.5)0.005
FPG (mg/dl; mean ± SD)86 (7)g,h,i106 (5)h,j95 (11)g,i,j108 (16)h,j94 (13)<0.001
2h-PG (mg/dl; mean ± SD)101 (22)g,8,i112 (18)h,i,j164 (16)g,i,j229 (38)g,h,j128 (45)<0.001
  • a Tests for trend using parametric, rank-based, or χ2 tests as appropriate.

  • BMI, body mass index; IQR, interquartile range.

  • b To accommodate low cell expectancies (<5 per cell), normal glucose tolerance, IFG, and IGT were collapsed for significance testing.

  • c Data available for n = 881 patients only; the combined P value is P = 0.241.

  • d In patients who have undergone KTx (n = 797).

  • e Available for n = 551 patients only.

  • f Available for n = 514 patients only.

  • g Post hoc analyses (Bonferroni): P < 0.05 versus IFG

  • h P < 0.05 versus IGT

  • i P < 0.05 versus diabetes

  • j P < 0.05 versus normal.