Table 4.

Summary of safety events (modified intent-to-treat analysis set)

EventQW (n = 108), n (%)Q2W (n = 107), n (%)Q4W (n = 215), n (%)
Deaths4 (4)3 (3)9 (4)
Thromboembolic vascular events3 (3)5 (5)7 (3)
Serious adverse events24 (22)28 (26)56 (26)
Treatment-emergent adverse events84 (78)77 (72)170 (79)
Discontinuations13 (12)15 (14)41 (19)
Discontinued for adverse events3 (3)4 (4)11 (5)
Transfusions4 (3.7)6 (5.7)14 (6.5)
Hypertension (new onset/worsening)13 (12)14 (13)26 (12)
Dialysis2 (2)2 (2)4 (2)