Table 2.

Relative risk of development of hypertension and proteinuria on the basis of baseline risk factors (n = 46)

Hypertension in 3 DaysHypertension OverallProteinuria
Age ≥57 yr1.57 (1.01 to 2.43)1.09 (0.87 to 1.36)1.09 (0.45 to 2.61)
Age ≥65 yr1.41 (0.98 to 2.02)1.01 (0.75 to 1.35)0.88 (0.50 to 1.56)
Overweight (BMI > 25)1.05 (0.60 to 1.62)1.07 (0.84 to 1.37)0.48 (0.20 to 1.16)
History of HTN1.10 (0.78 to 1.79)1.07 (0.86 to 1.34)1.13 (0.44 to 2.94)
Family history of HTN or cardiovascular disease1.09 (0.64 to 1.85)1.11 (0.80 to 1.52)0.86 (0.30 to 2.43)
45-mg starting dosea1.12 (0.72 to 1.74)1.06 (0.84 to 1.34)3.18 (1.43 to 7.08)
HTN in 3 days————0.90 (0.37 to 2.21)
HTN overall————0.90 (0.26 to 3.07)
Grade 3 HTN————1.30 (0.54 to 3.10)
Proteinuria0.95 (0.60 to 1.50)0.98 (0.76 to 1.26)——
  • Values in table are relative risk (95% confidence interval). BMI, body mass index; HTN, hypertension.

  • a Reference dose 30 mg.