Table 1.

Main clinical characteristics and baseline data as a function of plasma dp-ucMGP levels

All[dp-ucMGP] ≤ 921 pM[dp-ucMGP] > 921 pMP
n1075354
Age, yr67 ± 1365 ± 1370 ± 110.049
Male gender, n (%)64 (60)35 (66)29 (54)0.193
Body mass index, kg/m228 ± 627 ± 628 ± 60.421
SBP, mmHg154 ± 27149 ± 25158 ± 280.075
DBP, mmHg80 ± 1280 ± 1278 ± 120.447
Diabetes, n (%)45 (42)23 (43)22 (41)0.781
Smoking habit, n (%)a40 (39)20 (38)20 (39)0.937
Previous CVD, n (%)35 (33)18 (34)17 (31)0.784
Coumarin use, n (%)6 (5.6)06 (11.1)0.027
Ca phosphate binder use, n (%)43 (40)19 (36)24 (44)0.365
Vitamin D use, n (%)41 (38)16 (30)25 (46)0.09
CKD stage, n (%)0.004
    24 (3.7)4 (7.5)0
    330 (28)22 (41.5)8 (14.8)
    425 (23.4)10 (18.9)15 (27.8)
    58 (7.5)3 (5.7)5 (9.3)
    5D40 (37.4)14 (26.4)26 (48.1)
Calcium, mmol/L2.29 ± 0.182.31 ± 0.192.28 ± 0.170.443
Phosphate, mmol/L1.30 ± 0.471.31 ± 0.431.30 ± 0.500.896
Intact PTH, pg/ml123 ± 119 (79; 43 to 164)129 ± 135 (80; 46 to 151)117 ± 102 (78; 40 to 200)0.609
Hemoglobin, g/dL12 ± 1.712 ± 1.511 ± 1.6<0.0001
Albumin, g/L36 ± 637 ± 635 ± 50.102
C-reactive protein, mg/L11 ± 24 (3.5; 1.3 to 8.9)5 ± 6 (2.7; 1.1 to 6.7)16 ± 33 (4.0; 1.5 to 14.7)0.042
Triglycerides, mmol/L2.1 ± 1.4 1.7 (1.2 to 2.7)2.0 ± 1.6 1.5 (1.1 to 2.3)2.2 ± 1.2 1.9 (1.3 to 2.9)0.082
Total cholesterol, mmol/L4.9 ± 1.214.9 ± 1.34.9 ± 1.10.907
Aortic calcification score on CTb3.4 ± 3.2 (2.28; 0.9 to 4.7)2.4 ± 2.9 (1.2; 0.5 to 3.8)4.4 ± 3.1 (3.7; 1.9 to 6.7)<0.0001
Aortic calcification score on x-rayc7.3 ± 6.7 (6.0; 2.0 to 11)4.9 ± 5.4 (3.0; 0 to 8.0)9.4 ± 7.0 (9.0; 4.0 to 14)0.001
[dp-ucMGP], pM1100 ± 713539 ± 2051652 ± 591
  • Data are given as means ± SD (median; percentiles 25 to 75) for variables with a non-Gaussian distribution or as the number (percentage) for binary variables. SBP, systolic blood pressure; DBP, diastolic blood pressure; CVD, cardiovascular disease; Ca, calcium-containing; PTH, parathyroid hormone.

  • a n = 103.

  • b n = 101.

  • c n = 91.