Table 2.

Relationship between UPIIINP/Cr and patients' clinical and biologic features at inclusion

VariableUPIIINP/Cr
ValueP
Age, yr, r0.200.004
Male/female, ng/mmol, mean ± SD660 ± 1020/650 ± 8800.42
Caucasian/black, ng/mmol, mean ± SD630 ± 910/830 ± 12100.49
BMI, kg/m2, r (n = 99)−0.040.66
Creatinine, μmol/L, r0.36<0.0001
eGFR, ml/min per 1.73 m2, r−0.38<0.0001
CKD stages, ng/mmol mean ± SD
    eGFR ≥ 60 ml/min per 1.73 m2500 ± 860
    30 ≤ eGFR < 60 ml/min per 1.73 m2540 ± 720
    15 ≤ eGFR < 30 ml/min per 1.73 m2730 ± 670
    eGFR < 15 ml/min per 1.73 m21770 ± 1680
CKD etiology, ng/mmol, mean ± SDa
    Glomerular disease470 ± 740
    Vascular disease980 ± 12200.022
    Diabetic nephropathy770 ± 5700.046
    Interstitial/obstructive nephropathy1070 ± 13400.0011
    Unknown etiology500 ± 5300.92
Proteinuria, g/24 h, r0.080.24
Hypertension −/+, ng/mmol, mean ± SD640 ± 1000/670 ± 10000.92
ACEI/ARB −/+, ng/mmol, mean ± SD790 ± 1530/470 ± 5000.13
Blood pressure systolic/diastolic, r0.12/0.140.10/0.06
Diabetes mellitus −/+, ng/mmol, mean ± SD670 ± 1010/590 ± 4700.39
Ischemic heart disease −/+, ng/mmol, mean ± SD610 ± 850/1240 ± 16300.023
Liver disease −/+, ng/mmol, mean ± SD630 ± 910/1080 ± 13800.26
  • BMI, body mass index; eGFR, estimated glomerular filtration rate estimated using the Modification of Diet in Renal Disease simplified formula; ACEI/ARB, angiotensin-converting enzyme inhibitor/angiotensin II receptor blockers.

  • a. Glomerular disease versus other.