Table 1.

Subject characteristics

CharacteristicTotal[Na+] < 135 mmol/L[Na+] >135 mmol/LP
Number of patients (%)140859 (4.2)1349 (95.8)
Mean (SD) age (years)61.4 (10.7)67.8 (13.0)61.1 (10.5)<0.001
    range23 to 9732 to 9723 to 89
Mean (SD) T-score−2.3 (1.1)−2.6 (1.2)−2.3 (1.1)0.03
    range−6.5 to 0.9−5.6 to −0.2−6.5 to 0.9
Osteoporosis (%) (T-score < −2.5)44.957.644.30.04
Osteoporosis risk factors (%)
    amenorrhea83.981.484.00.59
    dairy servings <3/wk42.325.443.0<0.01
    alcohol >5 units/wk18.08.518.50.05
    maintenance steroids6.43.46.50.34
    ever smoked18.318.618.30.95
    family history10.35.110.50.18
    liver disease0.71.70.70.36
Treatment for osteoporosis (%)
    calcium33.039.032.80.32
    vitamin D8.313.68.10.14
    antiresorptive21.928.821.60.19
    hormonal replacement therapy9.611.99.50.54
Mean (SD) [Na+] (mmol/L)140.6 (3.0)132.2 (1.8)141.0 (2.4)<0.001
    range127 to 153127 to 134135 to 153
Mean (SD) eGFR (ml/min/1.73 m2)68.8 (12.3)66.9 (14.4)68.9 (12.2)0.43
    range20 to 8929 to 8820 to 89