Table 1.

Illustrative example of the effect of weighting in changing a subject’s contribution to an analysis

Future Dose
12,000 Units per 2 wk (Dose Category 1)40,000 Units per 2 wk (Dose Category 3)
Patient factors
    current dose, units per 2 wk20,000 (dose category 2)30,000 (dose category 3)
    current hemoglobin, g/dl10.410.4
    albumin, g/dl3.63.6
    TSAT, %19.219.2
    no. of recent hospitalizations11
Predicted probability of future dose given patient factors, %1080
Weight calculation1 divided by the probability of (dose given patient factors)1 divided by the probability of (dose given patient factors)
Contribution to analysisIncreased by 10Increased by 1.25