Table 1.

Baseline characteristics of patients at the time of hospital admission according to estimated CrC (n = 1078)

Characteristics≤45 ml/min (n = 152)45 to 60 ml/min (n = 198)>60 ml/min (n = 728)
Age in years (SD)75 (7)70 (8)58 (10)a
Gender—male (%)75 (49)129 (65)616 (85)b
Previous coronary artery disease (%)104 (68)116 (59)313 (43)b
Previous vascular disease (%)54 (36)53 (27)108 (15)b
Previous congestive heart failure (%)33 (22)15 (8)17 (2)b
Hypertension (%)120 (79)113 (57)312 (43)b
Smoking status active (%)20 (13)51 (26)265 (36)b
Dyslipidemia (%)106 (70)128 (64)431 (59)b
Diabetes (%)43 (28)41 (21)133 (18)b
Chronic obstructive lung disease (%)26 (17)32 (16)75 (10)b
Mean GFR in ml/min (SD)34 (7)53 (4)88 (23)a
Mean body mass index in kg/m2 (SD)23 (4)25 (4)28 (6)a
Median maximal CK (IQRc)161 (71 to 459)252 (97 to 964)356 (118 to 1143)a
Median cardiac troponin T (IQR)0.19 (0.01 to 1.07)0.45 (0.01 to 2.31)0.42 (0.01 to 1.80)a
Abnormalities on baseline ECG (%)87 (57)119 (60)413 (57)
Thrombolysis criteria on baseline ECG (%)32 (21)63 (32)235 (32)b
Diagnosis of MI (%)69 (45)117 (59)449 (62)b
Heart failure during hospitalization (%)34 (22)30 (15)47 (6)b
Use of antiplatelet agents before admission (%)95 (63)111 (56)298 (41)b
Use of warfarin before admission (%)16 (10)12 (6)19 (3)b
Use of β-blockers before admission (%)69 (45)78 (39)219 (30)b
Use of lipid-lowering agents before admission (%)82 (54)99 (50)304 (42)b
Use of ACE inhibitors/ARBs before admission (%)66 (43)65 (33)183 (25)b
  • a ≤0.05 by Kruskall–Wallis test for a difference between the three groups.

  • b P ≤ 0.05 by χ2 for a difference between the three groups.

  • c IQR, interquartile range.