Table 2.

Results from univariable and multivariable linear regression analyses^a of 6-mo change in β2M in HDF patients

Determinant	Univariable Regression		Multivariable Regression
Determinant	B^b	95% CI	B	95% CI
Gender (male)	1.3	−2.0 to 4.6
Age (per 10 yr)	0.2	−0.9 to 1.3
History of cardiovascular disease	2.5	−0.7 to 5.7	1.9	−1.3 to 5.2
Diabetes mellitus	2.7	−1.0 to 6.3	1.7	−2.1 to 5.5
Dialysis vintage (per yr)	−0.4	−0.9 to 0.2
Body mass index (per kg/m²)	0.0	−0.3 to 0.3
Arteriovenous fistula	0.2	−3.5 to 3.9
Convective volume (per L/treatment)	0.1	−0.3 to 0.6	0.3	−0.2 to 0.7
Dialysis frequency (per session/wk)	−6.3	−12.7 to 0.1	−3.7	−10 to 3.0
GFR (per ml/min/1.73 m²)	0.9	0.5 to 1.4^c	0.9	0.4 to 1.5^c
Serum albumin (per g/dl)	−0.2	−0.7 to 0.2

↵a Adjusted for participating center.
↵b The regression coefficient (B) reflects the change in β2M levels between baseline and 6 mo. Positive values of B indicate smaller decreases in β2M during the study period.
↵c P < 0.001.