Table 5.

Area under ROC curve (95% CI) of urinary NGAL for AKI, stratified by preoperative eGFR (AKI has been redefined as an increase in serum creatinine by >50% above baseline within 7 days of surgery)

eGFR <30 ml/mineGFR 30–60 ml/mineGFR 60–90 ml/mineGFR 90–120 ml/mineGFR >120 ml/min
After CPB0.23 (0.01 to 0.44)0.58 (0.44 to 0.71)0.64a (0.52 to 0.76)0.64a (0.50 to 0.78)0.18 (0.00 to 0.46)
3 h0.49 (0.21 to 0.76)0.61 (0.48 to 0.75)0.68a (0.54 to 0.81)0.67a (0.53 to 0.80)0.28 (0.00 to 0.73)
18 h0.45 (0.05 to 0.85)0.55 (0.37 to 0.74)0.69a (0.58 to 0.80)0.69a (0.53 to 0.85)0.37 (0.16 to 0.58)
24 h0.65 (0.34 to 0.96)0.54 (0.35 to 0.74)0.62 (0.49 to 0.73)0.71a (0.56 to 0.87)0.31 (0.09 to 0.54)
  • eGFR calculated by Cockcroft-Gault equation.

  • a P < 0.05.