Table 3.

Univariate and multivariate logistic analyses of the factors at biopsy that predicted progression during follow-up in patients with eGFR ≥60

VariableUnivariateMultivariate
5 Yr (n = 98)10 Yr (n = 60)5 Yr (n = 98)10 Yr (n = 60)
POR (95% CI)POR (95% CI)POR (95% CI)POR (95% CI)
eGFRNSNSNSNS
Urinary protein excretion (≥1 g/d)NS<0.017.1 (3.8 to 24.0)NSNS
HypertensionNSNSNSNS
Mesangial proliferation (>50%)NSNSNSNS
Cellular/fibrocellular crescentNS<0.018.0 (5.8 to 27.2)NS<0.0510.4 (1.1 to 48.2)
Segmental glomerular sclerosisNS<0.055.2 (1.3 to 16.0)NSNS
Global glomerular sclerosis (>25%)NS<0.058.0 (3.8 to 29.2)NSNS
Interstitial fibrosis (>25%)NSNSNSNS
Glomerular densityNS<0.014.7 (3.1 to 11.7)NS<0.0523.1 (1.7 to 143.7)
  • CI, confidence interval; OR, odds ratio.