Table 2.

CRP SNP allele frequencies for African Americans from NHANES III and AASK participants

CRP SNPsLocationAllelesAllele FrequenciesP Valuea
NHANES III (n = 450)AASK (n = 642)
rs28086303'-flanking regionA86%83%0.03b
G14%17%
rs12053'-flanking regionA21%18%0.03b
G79%82%
rs30930665'-flanking regionA24%22%0.3
C76%78%
rs1417938Intron 1A87%88%0.3
T13%12%
rs30930585'-flanking regionA84%81%0.08
T16%19%
rs1800947cExon 2C1%1%0.6
G99%99%
  • a Unadjusted for multiple comparisons.

  • b Not statistically significance at an α = 0.008 level after applying a Bonferroni correction (α = n/6).

  • c Data for rs1800947 are for all NHANES III African-Americans participants with DNA (n = 2108) because the data user agreement does not allow outputs with counts less than 5.