Table 2.

Use of cinacalcet hydrochloride and concomitant medications for secondary hyperparathyroidism

Group SGroup L
Baseline (n = 56)Week 12 (n = 55)Week 26 (n = 53)Week 52 (n = 49)Baseline (n = 25)Week 12 (n = 24)Week 26 (n = 21)Week 52 (n = 19)
Cinacalcet hydrochloride (mg/d)29.3 ± 9.932.7 ± 13.236.7 ± 14.528.7 ± 10.035.7 ± 19.942.8 ± 20.9
Intravenous vitamin D sterols
    subjects (%)7165626572545268
    calcitriol dose equivalentsa (μg/wk)2.18 ± 1.072.28 ± 1.162.32 ± 1.252.39 ± 1.333.06 ± 1.653.11 ± 1.372.86 ± 1.303.32 ± 2.00
Oral vitamin D sterol use (%)2125252912212932
Calcium carbonate
    subjects (%)5973798240756253
    calcium carbonate dose (mg/d)2506 ± 10672737 ± 11442779 ± 13702755 ± 14082030 ± 8682044 ± 8052023 ± 8312150 ± 1156
Sevelamer hydrochloride
    subjects (%)6864646572676763
    sevelamer hydrochloride dose (mg/d)3026 ± 10483100 ± 9802977 ± 10192930 ± 10693167 ± 12222878 ± 12242942 ± 13512625 ± 1517
  • Plus-minus values are mean ± SD.

  • a 1.5 μg of calcitriol = 10 μg of maxacalcitol.