Table 2.

Time course of urinary protein excretion (g/24 h) in individual patients with idiopathic MN from entry into the study (baseline) to 24 months

Patient No.Month 4BaselineMonth 3Month 6Month 9Month 12Month 18Month 24ΔProteinuriab Month 12ΔProteinuria Month 18ΔProteinuria Month 24
111.0514.236.834.484.436.792.692.56−7.43−11.54−11.67
2a10.438.057.199.478.1314.40+6.35
315.6813.696.365.306.404.647.241.93−9.43−6.45−11.76
410.5415.4612.1812.6510.563.230.121.60−12.23−15.34−13.86
56.7011.878.7913.774.063.915.033.01−7.96−6.84−8.86
66.405.731.111.511.091.591.822.01−4.14−3.91−3.72
7a5.239.9511.698.56
813.8012.7614.338.037.237.217.915.70−5.55−4.86−7.06
910.509.8811.5419.426.736.246.492.70−3.63−3.38−7.18
1020.008.595.831.600.380.310.050.20−8.28−8.54−8.40
1110.958.338.716.805.573.151.680.35−5.18−6.64−7.97
128.8111.331.521.000.760.500.230.14−10.83−11.10−11.19
1316.8019.179.476.310.831.340.060.28−17.82−19.11−18.89
148.147.023.131.931.330.760.630.65−6.26−6.38−6.37
1514.8612.1214.168.253.015.075.963.44−7.05−6.16−8.67
1610.087.814.582.052.222.002.161.53−5.81−5.65−6.28
1716.6316.276.453.021.9410.740.581.74−5.53−15.69−14.53
1814.7726.468.4914.9011.286.425.962.98−20.04−20.50−23.48
199.328.491.352.252.171.340.370.17−7.14−8.12−8.31
205.819.883.091.290.390.540.305.63−9.34−9.58−4.25
Mean11.3311.857.346.634.134.222.742.03−7.73−9.43−10.14
SD4.114.854.115.283.443.782.841.715.475.125.04
Median10.5210.647.015.813.013.231.751.84−7.14−7.48−8.54
  • a Patients 2 and 7 were discontinued from the study.

  • b ΔProteinuria = months 12, 18, and 24 proteinuria − baseline proteinuria.