Table 5.

Clinical characteristics of patients who experienced renal, cerebrovascular, or cardiovascular events

MenWomen
No Clinical Events (n = 73)Experienced Clinical Events (n = 48)No Clinical Events (n = 271)Experienced Clinical Events (n = 70)
Patients with eGFR data, n734827170
    age at baseline eGFR, mean (SD), years31 (11)39 (15)b38 (13)44 (12)b
    median (25th, 75th), years29 (23, 39)36 (27, 49)36 (27, 48)43 (37, 51)
    eGFRa at baseline, mean (SD)97 (22)81 (31)b97 (22)88 (21)b
    median (25th, 75th)97 (83, 113)89 (58, 100)100 (80, 112)86 (72, 104)
57.7, 99.8
    eGFRa slope, mean (SD), per year−2.2 (2.33)−3.1 (2.46)c−0.4 (1.37)−1.0 (1.41)b
    median (25th, 75th)−1.9 (−4.0, −0.2)−2.8 (−4.2, −1.7)−0.4 (−1.4, 0.4)−1.0 (−1.7, 0.0)
Patients with baseline UP/Cr data, n371116018
    UP/Cr, baseline mean (SD)1.0 (1.1)1.7 (1.4)0.8 (1.2)0.7 (0.8)
    median (25th, 75th)0.8 (0.2, 1.5)1.4 (0.8, 3.5)0.3 (0.1, 1.0)0.3 (0.1, 1.1)
Patients with averaged UP/Cr data, n734827170
    UP/Cr, averaged mean (SD)0.9 (0.9)1.4 (1.4)b0.8 (1.1)1.1 (1.5)
    median (25th, 75th)0.7 (0.2, 1.3)1.0 (0.4, 2.0)0.2 (0.1, 1.1)0.5 (0.1, 1.5)
BP, n684025666
    systolic BP, averaged mean (SD), mmHg126 (10)129 (14)122 (14)125 (15)
    median (25th, 75th)126 (119, 131)128 (119, 138)121 (112, 133)124 (113, 137)
    diastolic BP, averaged mean (SD), mmHg76 (9)76 (8)75 (9)77 (10)
    median (25th, 75th)77 (72, 83)76 (72, 82)75 (69, 82)77 (70, 84)
Reported history of ACEi/ARB use, n (%)14 (88)12 (71)49 (73)15 (54)
  • “Averaged” data reflect the average of all values reported within 6 months of the date of the first eGFR assessment to the most recent assessment.

  • a eGFR data are expressed as ml/min per 1.73 m2.

  • b P < 0.05 by t test.

  • c P = 0.054 by t test.