Table 2.

Logistic regression analysis to determine the independent predictors for the presence of significant RAC

Independent PredictorsModel 1aModel 2b
HR (95% CI)PHR (95% CI)P
Age, every 1-year increase1.10 (1.04 to 1.16)0.0011.09 (1.02 to 1.16)0.01
Gender (reference male)3.02 (1.29 to 7.06)0.01
History of cardiovascular disease (reference no)c4.49 (2.16 to 9.33)<0.0014.38 (1.93 to 9.93)<0.001
CAC score (reference 0 to 10)<0.001
    11 to 991.23 (0.26 to 5.90)0.79
    100 to 3992.72 (0.78 to 9.44)0.12
    ≥40011.62 (3.35 to 40.39)<0.001
  • a Variables considered for inclusion in model 1: Age, gender, history of cardiovascular disease, serum phosphorus, serum 25(OH)D, and lipid-lowering agents; c statistic 0.76.

  • b Variables considered for inclusion in model 2: Model 1 plus CAC score; c statistic 0.77.

  • c History of cardiovascular disease was defined as the presence of any one of the following: previous myocardial infarction, stroke, coronary revascularization, or typical angina (based on Rose questionnaire).