Event | Denominator | Fixed-Effects Analysis | Random-Effects Analysis | ||
---|---|---|---|---|---|

Test for Heterogeneity | Estimated Rate (95% CI) | Estimated Rate (95% CI) | SD Estimate^{a} | ||

Induced abortions | Number of pregnancies | <0.001 | 7.2% (6.0%, 8.4%) | 5.9% (3.2%, 8.6%) | 5.6% |

Spontaneous abortions | Number of pregnancies without induced abortions | <0.001 | 16.6% (14.7%, 18.5%) | 16.0% (12.1%, 19.9%) | 7.6% |

Stillbirths | Number of pregnancies without induced abortions | 0.001 | 4.0% (2.9%, 5.1%) | 3.6% (2.0%, 5.2%) | 2.2% |

Neonatal deaths | Number of pregnancies without induced abortions | 0.050 | 2.8% (1.9%, 3.8%) | 2.5% (1.2%, 3.8%) | 1.5% |

Unsuccessful pregnancies | Number of pregnancies without induced abortions | 0.025 | 23.0% (20.3%, 25.6%) | 23.4% (19.5%, 27.3%) | 4.7% |

Intra Uterine Growth Retardation (IUGR) | Number of pregnancies without induced abortions | <0.001 | 14.3% (12.4%, 16.2%) | 12.7% (8.8%, 16.7%) | 6.8% |

Premature Birth Rate | Number of live births | <0.001 | 37.1% (34.8%, 39.4%) | 39.4% (32.4%, 46.4%) | 17.6% |

↵a To compute an estimate of the random-effects SD, which depends on the value of the complication rate, the central value from the random-effects model (i.e., the random-effects estimated rate) was used in the calculation.