Table 4.

Adjusted hazard ratios for CV events for clinical classes of eGFR, split for UAE < 30 mg/24 h (MA−) and UAE ≥ 30 mg/24 h (MA+)

eGFR byeGFR ≥ 90eGFR 89 to 60eGFR < 60
MDRD
    MA+2.7 (1.1 to 6.6)1.5 (0.8 to 2.8)2.5 (1.2 to 5.2)
    MA−11.4 (0.8 to 2.3)0.8 (0.4 to 1.6)
CKD EPI
    MA+1.3 (0.4 to 2.9)1.4 (0.7 to 2.7)2.1 (1.0 to 2.4)
    MA−11.1 (0.6 to 1.9)0.8 (0.4 to 1.6)
CysC
    MA+1.7 (0.9 to 3.1)1.4 (0.9 to 2.3)2.1 (1.0 to 4.3)
    MA−11.1 (0.8 to 1.5)1.5 (0.9 to 2.4)
Combi
    MA+1.4 (0.7 to 3.0)1.1 (0.7 to 1.9)1.6 (0.8 to 3.1)
    MA−10.8 (0.6 to 1.2)0.8 (0.5 to 1.5)
24-hour creatinine clearance
    MA+1.2 (0.7 to 2.3)1.8 (1.1 to 2.9)2.1 (1.1 to 4.0)
    MA−11.1 (0.8 to 2.6)1.2 (0.8 to 2.9)
  • CV risk factors: body mass index, systolic blood pressure, total cholesterol (mmol/L), fasting glucose (mmol/L), smoking status, history of CV disease.