Table 3.

Biochemical and fracture data at 2 to 4 wk and 1 yr after transplantation

Parameter2 to 4 Wk1 Yr
Transplant TypeTreatment ReceivedTransplant TypeTreatment Received
KKPBPCKKPBPC
Calcium (2.13 to 2.63 mmol/L; mean ± SE)2.40 ± 0.022.41 ± 0.022.43 ± 0.02a2.37 ± 0.022.42 ± 0.022.40 ± 0.022.42 ± 0.022.41 ± 0.02
Phosphate (0.65 to 1.05 mmol/L; mean ± SE)0.82 ± 0.030.80 ± 0.040.79 ± 0.030.86 ± 0.041.03 ± 0.030.98 ± 0.041.00 ± 0.031.03 ± 0.03
iPTH (1.0 to 6.8 pmol/L; median [range])10.5 (0 to 167)10.5 (1 to 209)10.1 (0 to 167)11.3 (0 to 209)7.5 (0 to 394)7.0 (2 to 70)8.3 (0 to 394)b5.6 (0 to 31)
Osteocalcin (3.7 to 10.0 μg/L; median [range])4.5 (1 to 55)4.7 (0.7 to 32)5.5 (1 to 55)3.6 (1 to 26)4.8 (1 to 45)4.1 (1 to 17)3.6 (1 to 32)a4.9 (1 to 45)
ALP (30 to 115 U/L; median [range])82 (20 to 425)94 (39 to 352)95 (20 to 425)b78 (38 to 363)72 (29 to 221)64 (35 to 341)69 (37 to 341)69 (29 to 221)
Urinary DPD/Cr (2.3 to 5.4 nmol/mmol male, 3.0 to 7.4 nmol/mmol female; mean ± SE)7.8 ± 0.49.4 ± 0.5a8.9 ± 0.4a7.5 ± 0.45.1 ± 0.44.9 ± 0.34.9 ± 0.35.2 ± 0.4
25(OH)D (31 to 107 nmol/L; mean ± SE)54 ± 238 ± 2a48 ± 248 ± 365 ± 366 ± 463 ± 370 ± 4
Calcitriol (36 to 120 pmol/L; mean ± SE)95 ± 778 ± 894 ± 885 ± 7132 ± 8115 ± 9126 ± 8125 ± 9
Prevalent vertebral fracture (%)32455211a
Incident fracture, any site (%)916139
Incident vertebral fracture (%)69102
  • BP, bisphosphonate; C, calcitriol; K, kidney; KP, kidney-pancreas.

  • a P ≤ 0.05,

  • b P ≤ 0.01 for comparison.