Table 1.

Baseline subject characteristics

CharacteristicTotal Sample (n = 91)Cinacalcet-D (n = 48)Flex-D (n = 43)P Valuea
Age (yr)58.7 ± 14.557.9 ± 15.759.5 ± 13.10.61
Male [n (%)]53 (58)29 (60)24 (56)0.66
Race [n (%)]0.69
    African American35 (39)19 (40)16 (37)
    White28 (31)13 (27)15 (35)
    Hispanic25 (28)15 (31)10 (23)
    Other3 (35)1 (2)2 (5)
Dialysis duration (mo)47.4 ± 44.446.5 ± 34.948.4 ± 53.30.84
Log FGF23 (pg/ml)7.6 ± 1.77.9 ± 1.87.4 ± 1.60.19
    FGF23 (pg/ml)2631 (494–8263)3850 (787–8912)1306 (427–6546)0.15
PTH (pg/ml)611 ± 218595 ± 219628 ± 2190.48
P (mg/dl)5.3 ± 1.75.4 ± 1.75.2 ± 1.80.59
Ca (mg/dl)9.6 ± 0.59.6 ± 0.69.7 ± 0.40.54
Ca × P (mg2/dl2)50.3 ± 16.050.9 ± 15.049.6 ± 17.10.70
  • The χ2 test was used for comparisons of proportions among gender and race, whereas ANOVA was used for comparisons of age, dialysis duration, log FGF23, PTH, P, Ca, and Ca × P; these values are shown as mean ± SD.

  • The Wilcoxon rank-sum test was used to compare medians of untransformed FGF23; these values are shown as median and interquartile range.

  • a Comparison of Cinacalcet-D versus Flex-D treatment groups.