Table 2.

Renal findings in patients with monoclonal gammopathies and associated hemorrhagic complications

Percentage (n)Bleeding Complications (n)
Amyloid23.7 (35)0
Cast nephropathy62.2 (92)6a
Mixed amyloid and cast3.4 (5)0
LCDD0.7 (1)0
Intraglomerular crystal deposition0.7 (1)0
ATN2.7 (4)0
Other renal findingsb6.8 (10)0
  • ATN, acute tubular necrosis; LCDD, light chain deposition disease.

  • a Two of the six bleeding complications in patients with cast nephropathy were hematomas. One of these required radiologic intervention. The remaining four complications were significant hematuria and did not require radiologic intervention.

  • b Other renal findings included diabetic nephropathy; hypertensive damage; end-stage kidney; membranous nephropathy; and focal segmental glomerular sclerosis.