Table 4.

Summary of the most relevant clinical findings

Alteration inESRF or Death (3 years)Response to Plasma (outcome of episode = CR or PR/total of treated episodes)Good Kidney Transplantation Outcome (at 1 year)
CFH49 (77%)57 (63%)5 (29%)
CFI6 (60%)2 (25%)2 (33%)
C38 (67%)8 (57%)4 (57%)
THBD7 (54%)7 (88%)0
MCP1 (6%)28 (97%)3 (100%)
CFH Ab5 (63%)9 (75%)0
Non mut60 (50%)71 (69%)12 (41%)
Sporadic83 (49%)a139 (69%)19 (46%)
Familial53 (74%)43 (68%)7 (30%)
Children70 (48%)b131 (78%)c8 (33%)
Adults63 (67%)51 (53%)18 (45%)
  • a Comparison between sporadic and familial forms: P < 0.0001.

  • b Comparison between children and adults: P = 0.004.

  • c Comparison between children and adults: P < 0.0001.

    CR, complete remission; PR, partial remission.