Table 4.

Results of the multiple logistic regression analysis for determinants of GFR decliner in all subjects and those with and without diabetes a

Determinant bAll SubjectsSubjects with DiabetesSubjects without Diabetes
OR (95% CI)POR (95% CI)POR (95% CI)P
Baseline GFR (≥77.4 versus <77.4 ml/min/1.73 m2)1.34 (0.76 to 1.86)0.0871.49 (1.03 to 2.18)0.0360.87 (0.41 to 1.87)0.723
Baseline HbA1C
    <6.0%1.0 (reference)1.0 (reference)0.72 (0.23 to 2.27) c0.571
    6.0 to 6.9%1.31 (0.91 to 1.87)0.1431.42 (0.89 to 2.27)0.141
    ≥7.0%2.64 (1.77 to 3.94)0.0002.93 (1.76 to 4.87)0.000
Baseline SBP (≥127 versus <127 mmHg)1.56 (1.17 to 2.18)0.0031.50 (1.06 to 2.13)0.0231.94 (0.86 to 4.34)0.109
Baseline plasma TP (≤7.1 versus >7.1 g/dl)1.51 (1.10 to 2.06)0.0101.44 (1.02 to 2.01)0.0412.04 (0.99 to 4.23)0.055
Gender (female versus male)1.63 (1.10 to 2.40)0.0151.59 (1.02 to 2.45)0.0401.50 (0.61 to 3.70)0.582
  • a The analysis was performed with the GFR decliner as the dependent variable and age; BMI; gender; HbA1C; SBP; RASI use; baseline GFR; serum concentrations of HDL, LDL and TG; plasma TP; hemoglobin; and platelet as the independent variables.

  • b Median values were 77.4 ml/min/1.73 m2 for GFR, 127 mmHg for SBP, and 7.1 g/dl for plasma TP. OR, odds ratio; CI, confidence interval.

  • c HbA1C was not categorized but used as a continuous variable.