Table 2.

Eligibility and exclusion criteria

Eligibility criteria
    Age stratum (yr)/eligible eGFR range (ml/min per 1.73 m2)a
        21 to 44/20 to 70
        45 to 64/20 to 60
        65 to 74/20 to 50
Exclusion criteria
    institutionalized (e.g., prisoner, nursing home or skilled nursing facility resident)
    unable or unwilling to give consent
    unlikely or unable to participate in required study procedures
    New York Heart Association class III or IV heart failure (baseline)
    known cirrhosis
    known HIV infection and/or AIDS
    pregnant women
    previously received dialysis for {my]1 mo
    previous organ or bone marrow transplant
    received immunosuppressive or other immunotherapy for primary renal disease or systemic vasculitis within the past 6 mo
    previous chemotherapy or alkylating agents for systemic cancer other than non-melanoma skin cancer within 2 yr
    previous diagnosis of multiple myeloma or renal carcinoma
    polycystic kidney disease
    current participation in interventional clinical trial or in a research study
  • a Based on simplified Modification of Diet in Renal Disease (MDRD) equation.