Eligibility and exclusion criteria
Eligibility criteria |
Age stratum (yr)/eligible eGFR range (ml/min per 1.73 m2)a |
21 to 44/20 to 70 |
45 to 64/20 to 60 |
65 to 74/20 to 50 |
Exclusion criteria |
institutionalized (e.g., prisoner, nursing home or skilled nursing facility resident) |
unable or unwilling to give consent |
unlikely or unable to participate in required study procedures |
New York Heart Association class III or IV heart failure (baseline) |
known cirrhosis |
known HIV infection and/or AIDS |
pregnant women |
previously received dialysis for {my]1 mo |
previous organ or bone marrow transplant |
received immunosuppressive or other immunotherapy for primary renal disease or systemic vasculitis within the past 6 mo |
previous chemotherapy or alkylating agents for systemic cancer other than non-melanoma skin cancer within 2 yr |
previous diagnosis of multiple myeloma or renal carcinoma |
polycystic kidney disease |
current participation in interventional clinical trial or in a research study |
↵a Based on simplified Modification of Diet in Renal Disease (MDRD) equation.