Appendix.

Data from a patient who developed urosepsis resulting in lactic acidosis and acute kidney injurya

Parameter12
Na136136
K4.54.5
Cl106108
HCO32415
Ca3.33.3
P (mmol/L)1.02.0
Mg1.61.6
Albumin (g/dl)4.42.0
Lactate1.06.0
pH7.407.33
Pco2 (mmHg)4030
AG613
AGc619
ΔAG013
SIDa3937
SIDe3824
SIG113
  • a Column 1 represents the baseline data, and column 2 represents data obtained on admission to the ICU with fever and hypotension. The formulas used in calculating AG, AGc, SIDa, SIDe, and SIG are shown in Table 1. AG is calculated as Na − (Cl + HCO3). Note the effect of hypoalbuminemia on AG and ΔAG as well as the relationship between ΔAG and SIG. All values are in mEq/L except as indicated.