Table 4b.

Hazard ratios for MACE by univariate and multivariate Cox regression in the IL-6 cohorta

ParameterUnivariate Hazard Ratio (95% CI)P ValueMultivariate Hazard Ratio 95% (95% CI)P Value
Diabetes mellitus215 (1.65 to 2.80)0.0002.22 (1.66 to 2.95)0.000
CHD3.10 (2.27 to 4.25)0.0002.04 (1.45 to 2.85)0.000
Smoking current1.55 (1.09 to 2.20)0.0141.45 (1.00 to 2.08)0.048
LDL cholesterol (mmol/L)1.34 (1.24 to 1.58)0.0001.38 (1.22 to 1.55)0.000
IL-6 (pg/ml)1.15 (1.08 to 1.22)0.0001.08 (1.01 to 1.15)0.018
Age (yr)1.04 (1.03 to 1.02)0.0001.03 (1.01 to 1.04)0.000
Creatinine (μmol/L)1.00 (1.00 to 1.01)0.0001.01 (1.00 to 1.01)0.000
Systolic BP (mmHg)1.01 (1.00 to 1.02)0.0001.00 (0.99 to 1.01)0.385
Gender0.75 (0.57 to 0.99)0.0380.94 (0.73 to 1.25)0.653