Table 5.

Current clinical parameters in donors and matched two-kidney control subjectsa

ParameterDonor BMI CategorybDonorsTwo-Kidney Control SubjectsPc
Renal function
    GFR (ml/min per 1.73 m2; mean ± SD)Nonobese63 ± 1384 ± 180.0001
Obese64 ± 1387 ± 180.0001
    % with GFR <60Nonobese41.05.50.0001
Obese50.02.10.0001
BP
    SBP (mmHg; mean ± SD)Nonobese127 ± 15124 ± 200.251
Obese137 ± 18133 ± 130.454
    DBP (mmHg; mean ± SD)Nonobese81 ± 971 ± 110.0001
Obese86 ± 977 ± 100.003
    % with hypertensiondNonobese34380.486
Obese69620.61
Other CVD risk factors
    Total cholesterol (mg/dl; mean ± SD)Nonobese203 ± 34207 ± 360.351
Obese206 ± 26212 ± 380.623
    HDL cholesterol (mg/dl; mean ± SD)Nonobese60 ± 1858 ± 170.391
Obese51 ± 1350 ± 140.835
    % with abnormal HDL cholesteroleNonobese15240.066
Obese44360.592
    10-yr FRSNonobese5.05.10.893
Obese6.36.50.881
  • a Nonobese = BMI <30; obese = BMI ≥30. CVD, cardiovascular disease; DBP, diastolic BP; FRS, Framingham Risk Score; SBP, systolic BP.

  • b At time of donation

  • c Measured by t test for continuous variables and the χ2 test for categorical variables.

  • d SBP >140 mmHg, DBP >90 mmHg, or known diagnosis of hypertension.

  • e HDL <40 mg/dl for men, <50 mg/dl for women.