Table 3.

Multivariate model of factors associated with mortality, with groups based on ESA use during the baseline perioda

VariableNo ESA Use (n = 3143)On ESA Throughout (n = 1823)
HR95% CIPHR95% CIP
Age (per 10 yr)1.571.46 to 1.70<0.0011.531.41 to 1.65<0.001
Male1.251.06 to 1.480.011.140.96 to 1.350.13
Diabetes1.311.12 to 1.540.0010.940.79 to 1.120.49
GFR (per 5 ml/min)0.840.80 to 0.88<0.0010.930.88 to 0.970.001
Dialysis initiation1.941.58 to 2.38<0.0011.701.37 to 2.11<0.001
Absolute Hb (intercept; g/L)0.990.980 to 0.993<0.0010.990.980 to 0.993<0.001
Hb trend (slope; g/L per mo)0.960.93 to 0.990.0130.940.92 to 0.97<0.001
Residual SD (g/L)1.031.02 to 1.05<0.0011.021.01 to 1.040.008
  • a CI, confidence interval; HR, hazard ratio.