Table 1.

Main clinical characteristics and baseline data, as a function of vitamin D status

CharacteristicAll (n = 140)25D ≤ 16.7 ng/ml (n = 71)25D > 16.7 ng/ml (n = 69)P
Age, years67 ±1268 ±1366 ±120.299
Male gender, n (%)85(61)42(59)43(62)0.702
Body mass index, kg/m228 ±628 ±528 ±70.646
Systolic BP, mmHg153 ±26149 ±27157 ±250.089
Diastolic BP, mmHg81 ±1280 ±1282 ±120.387
Diabetes, n (%)59(42)32(46)27(38)0.317
Smoking habit, n (%)55(40)24(35)31(46)0.221
Presence of CVD, n (%)44(31)23(32)21(30)0.803
CKD stage, n (%)0.864
    211(8)6(8.5)5(7)
    336(26)20(28)16(23)
    437(26)18(25)19(28)
    510(7)6(8.5)4(6)
    5D46(33)21(30)25(36)
Calcium, mMol/L2.3 ±0.22.3 ±0.22.27 ±0.190.390
Phosphate, mMol/L1.3 ±0.41.3 ±0.51.3 ±0.40.635
iPTH, pg/ml (median)138 ±138150 ±152126 ±1220.537
(85)(99)(78)
Hemoglobin, g/L12 ±1.712 ±1.912 ±1.60.834
Albumin, g/L37 ±636 ±638 ±60.030
C-reactive protein, mg/L (median)11 ±2313 ±299 ±150.812
(3.5)(3.5)(3.3)
Total cholesterol, mMol/L4.9 ±1.25.0 ±1.24.7 ±1.00.066
Aortic calcification score on CT, %a (median)2.9 ±3.03.1 ±3.32.8 ±2.70.910
(1.8)(1.9)(1.7)
Aortic calcification score on x-ray (scale 0-24)bc (median)6.2 ±6.56.2 ±6.76.0 ±6.50.812
(4.0)(4.0)(4.0)
PWV, m/s14 ±415 ±414 ±40.701
Vitamin D supplementation, n (%)50(36)18(25)32(46)0.009
25-hydroxyvitamin D, ng/ml (median)20.5 ±13.610.8 ±3.930.5 ±12.9
(16.7)(10.7)(28.7)
  • Data are means ± SD and sometimes (median) for variables with non-Gaussian distribution, or number (frequency) for binary variables. BP, blood pressure; DBP, diastolic blood pressure; CVD, cardiovascular disease; CKD, chronic kidney disease; iPTH, intact-parathyroid hormone; CT, computed tomography; PWV, pulse wave velocity.

  • a n = 129;

  • b n =122;

  • c by lateral lumbar x-rays, as previously described.