Table 3.

Risk for death within 1 d of a hypoglycemia event, by glucose category and CKD

ParameterGlucose ≥70 mg/dl (No Hypoglycemia)Glucose <70 and ≥60 mg/dlGlucose <60 and ≥50 mg/dlGlucose <50 mg/dl
Inpatient
    no. of records1,156,23525,45311,69811,825
    no CKD
        OR (95% CI)a1.00 (reference)2.54 (2.13 to 3.03)3.79 (3.02 to 4.75)9.95 (8.58 to 11.53)
        no. of records728,13713,35256525699
        no. of death eventsb2870 (0.4)131 (1.0)80 (1.4)205 (3.6)
    CKD
        OR (95% CI)a1.12 (1.05 to 1.19)1.85 (1.49 to 2.28)4.10 (3.33 to 5.05)6.09 (5.12 to 7.23)
        no. of records428,09812,10160466126
        no. of death eventsb2114 (0.5)93 (0.8)99 (1.6)147 (2.4)
Outpatient
    no. of events810,42012,98058705725
    no CKD
        OR (95% CI)a1.00 (reference)4.34 (3.02 to 6.26)7.36 (4.66 to 11.63)13.28 (9.20 to 19.18)
        no. of records535,803732829332679
        no. of death eventsb524 (0.1)31 (0.4)20 (0.7)33 (1.2)
    CKD
        OR (95% CI)a1.09 (0.94 to 1.25)3.98 (2.65 to 5.99)3.28 (1.73 to 6.21)6.84 (4.41 to 10.62)
        no. of records274,617565229373046
        no. of death eventsb359 (0.1)25 (0.4)10 (0.3)22 (0.7)
  • a Odds ratio (OR) estimated from logistic regression models accounting for repeated glucose measures within individuals. All P ≤ 0.0001. Adjusted for confounders: Race, gender, age, CCI, cancer, diabetes, and CVD.

  • b Number (%) of 1-d death events by records in each subgroup.