Table 1.

Patient characteristics by CKD and hypoglycemia statusa

CharacteristicCKDPresence or Absence of HypoglycemiaSeverity of Hypoglycemia
No (GFR ≥60)Yes (GFR <60)Glucose ≥70 mg/dlGlucose <70 mg/dlGlucose ≥60 and <70 mg/dlGlucose ≥50 and <60 mg/dlGlucose <50 mg/dl
Total Patients173,05370,169204,08439,13817,351926212,525
Gender
    male165,408 (95.6)67,886 (96.7)195,304 (95.7)37,990 (97.1)16,763 (96.6)9017 (97.4)12,210 (97.5)
    female7645 (4.4)2283 (3.3)8780 (4.3)1148 (2.9)588 (3.4)245 (2.6)315 (2.5)
Race
    white137,613 (79.5)58,134 (82.8)166,652 (81.7)29,095 (74.3)13,058 (75.3)6883 (74.3)9154 (73.1)
    black33,774 (19.5)11,269 (16.1)35,385 (17.3)96,568 (24.7)4145 (23.9)2281 (24.6)3232 (25.8)
    other1666 (1.0)766 (1.1)2047 (1.0)385 (1.0)148 (0.9)98 (1.1)139 (1.1)
Age (median)61.00 ± 0.0373.00 ± 0.0464.00 ± 0.0367.00 ± 0.0666.00 ± 0.1068.00 ± 0.1268.00 ± 0.10
CCI
    085,435 (49.4)27,666 (39.4)98,044 (48.0)15,057 (38.5)6940 (40.0)3546 (38.3)4571 (36.5)
    158,895 (34.0)26,515 (37.8)70,878 (34.7)14,532 (37.1)6290 (36.3)3479 (37.6)4763 (38.0)
    ≥228,723 (16.6)15,988 (22.8)35,162 (17.2)9549 (24.2)4121 (23.8)2237 (24.2)3191 (25.5)
Diabetes
    no116,463 (67.3)34,756 (49.5)136,092 (66.7)15,127 (38.7)8983 (51.8)2883 (31.1)3261 (26.0)
    yes56,590 (32.7)35,413 (50.5)67,992 (33.3)24,011 (61.3)8368 (48.2)6379 (68.9)9264 (74.0)
Cancer
    no134,295 (77.6)50,844 (72.5)155,994 (76.4)29,145 (74.5)12,871 (74.2)6960 (75.1)9314 (74.4)
    yes38,748 (22.4)19,325 (27.5)48,090 (23.6)9993 (25.5)4480 (25.8)2302 (24.9)3211 (25.6)
CVD
    no123,515 (71.4)32,799 (46.7)135,177 (66.2)21,137 (54.0)10,083 (58.1)4746 (51.2)6308 (50.4)
    yes49,538 (28.6)37,370 (53.3)68,907 (33.8)18,001 (46.0)72,768 (41.9)4516 (48.8)6217 (49.6)
CKD
    no CKD173,053 (100)0 (0)150,892 (73.9)22,161 (56.6)10,780 (62.1)5095 (55.0)6286 (50.2)
    stage 3b0 (0)57,194 (81.5)45,287 (22.2)11,907 (30.4)4813 (27.7)2907 (31.4)4187 (33.4)
    stage 4c0 (0)8281 (11.8)5260 (2.6)3021 (7.7)994 (5.7)728 (7.9)1299 (10.4)
    stage 5d0 (0)4694 (6.7)2645 (1.3)2049 (5.2)764 (4.4)532 (5.7)753 (6.0)
  • a CCI, Charlson comorbidity index; CKD, chronic kidney disease; CVD, cardiovascular disease.

  • b GFR ≥30 and <60 ml/min per 1.73 m2.

  • c GFR ≥15 and <30 ml/min per 1.73 m2.

  • d GFR <15 ml/min per 1.73 m2.