Table 3.

Association of ADMA with all-cause and CVD mortalitya

ParameterAll-Cause MortalityCVD Mortality
HR (95% CI)PHR (95% CI)P
Unadjusted1.18 (1.04 to 1.35)0.0121.25 (1.06 to 1.47)0.007
Adjusted
    model 11.13 (0.99 to 1.29)0.0671.21 (1.02 to 1.29)0.023
    model 21.15 (1.00 to 1.31)0.0621.25 (1.05 to 1.48)0.027
    model 31.09 (0.99 to 1.26)0.0831.19 (1.00 to 1.42)0.034
  • a Hazard ratio (HR) presented per 1-SD (0.25 μmol) increase in ADMA. Model 1 adjusted for age, gender, race, and randomization assignments; model 2 adjusted for history of CVD, history of diabetes, smoking, DBP, LDL, HDL, CRP, and BMI in addition to variables in model 1; model 3 adjusted for GFR, proteinuria, and cause of kidney disease in addition to variables in model 2.