Table 4.

Unadjusted and adjusted OR (95% CI) of having CACS ≥400 across tertiles of serum AlkPhos in 137 MHD patientsa

ParameterSerum AlkPhos (IU/L)
First Tertile (<85; n = 45)Second Tertile (85 to 119; n = 46)Third Tertile (≥120; n = 46)
OR (95% CI)POR (95% CI)OR (95% CI)P
Unadjusted ORs1.96 (0.84 to 4.55)0.1201.00 (reference)3.52 (1.49 to 8.29)0.004
Adjusted ORs
    age2.22 (0.89 to 5.54)0.0901.00 (reference)4.63 (1.79 to 11.98)0.002
    age + gender2.27 (0.90 to 5.74)0.0801.00 (reference)5.98 (2.16 to 16.58)0.001
    age + gender + diabetes2.43 (0.93 to 6.37)0.0701.00 (reference)6.21 (2.17 to 17.76)0.001
    age + gender + diabetes + Charlson2.89 (1.05 to 7.96)0.0401.00 (reference)6.03 (2.09 to 17.39)0.001
    age + gender + diabetes + Charlson + vintage3.01 (1.01 to 8.99)0.0501.00 (reference)5.75 (1.84 to 18.02)0.003
    age + gender + diabetes + Charlson + vintage + IL-6 + AST2.41 (0.79 to 7.39)0.1201.00 (reference)5.03 (1.55 to 16.34)0.007
  • a Log-transformed value of dialysis vintage, IL-6, and AST were used in these analyses. CI, confidence interval; OR, odds ratio.