Table 2.

Comparison between kidney biopsies performed at diagnosis and after long-term treatment with CNI in the nine patients who were rebiopsed before rituximab treatment

Patient No.TimeBiopsy at DiagnosisBiopsy After Long-Term Treatment with CNI
No. of GlomeruliGlom Scler %Int Scler %No. of GlomeruliGlom Scler %Int Scler %
181128021100
24990011125
338110013105
4471300900
55314001000
6352200112015
764100013010
88313008155
9791600121623
Mean58.7 ± 18.613.3 ± 3.80.11 ± 0.33012 ± 3.79.2 ± 7.5a7 ± 7.8b
  • Time between the two kidney biopsies in months. Glom sclera, percentage of sclerosed glomeruli; Int sclera, percentage of interstitial fibrosis.

  • a P = 0.028.

  • b P = 0.026.