Table 8.

Biopsy results that potentially do or do not modify treatmenta

VariableModifies Treatment, n (%)Does Not Modify Treatment, n (%)Total nP
Clinical presentation
    AKI82(52)27(35)1090.01
    CKI21(13)35(45)56<0.001
    NS28(18)3(4)310.003
    AKI and NS18(12)4(5)220.116
    proteinuria5(3)8(10)130.03
    proteinuria and hematuria3(2)0(0)3
    hematuria0(0)1(1)1
    total157(67)78(33)235
History of chronic kidney injury43(41)32(68)750.002
Microhematuria84(70)19(40)103<0.001
Positive ANCA40(49)5(16)45<0.001
  • Biopsies with multiple diagnoses are included. See text for listing of renal biopsy diagnoses predicted to modify specific therapy on which this analysis was based. AKI, acute kidney injury; CKI, chronic-progressive kidney injury; NS, nephrotic syndrome; ANCA, anti-neutrophil cytoplasmic antibody.