Table 2.

Treatment characteristics and clinical outcomes of PD-associated peritonitis caused by Pseudomonas or other organisms in Australia, 2003 through 2006. Results are expressed as number (%) or median days [interquartile range]a

OutcomePseudomonas Peritonitis (n = 191 Episodes)Non-Pseudomonas Peritonitis (n = 3403 Episodes)P
Treatment
    change to second antibiotic regimen (n [%])126 (66)1884 (55)0.005
    time to second antibiotic regimen (d; median [IQR])2.00 (1.00 to 4.00)3.00 (2.00 to 5.00)0.030
    change to third antibiotic regimen (n [%])48 (25)449 (13)<0.001
    time to third antibiotic regimen (d; median [IQR])6.00 (4.00 to 11.00)7.00 (4.00 to 10.00)0.400
    total antibiotic treatment duration (d; median [IQR])16.00 (9.75 to 23.00)14.00 (8.00 to 19.00)0.001
Relapse (n [%])17 (9)485 (14)0.040
Hospitalization
    n (%)150 (79)2354 (69)0.006
    duration (d; median [IQR])9.00 (5.00 to 20.00)6.00 (3.00 to 11.00)<0.001
Catheter removal
    n (%)84 (44)691 (20)<0.001
    time to occurrence (d; median [IQR])5.50 (3.00 to 11.00)6.00 (3.00 to 13.00)0.400
Temporary hemodialysis
    n (%)20 (10)132 (4)<0.001
    time to occurrence (d; median [IQR])7.50 (4.25 to 12.50)6.00 (3.00 to 11.50)0.500
    duration (d; median [IQR])73.50 (51.00 to 109.50)67.00 (20.50 to 103.00)0.300
Permanent hemodialysis
    n (%)66 (35)569 (17)<0.001
    time to occurrence (d; median [IQR])6.00 (4.00 to 11.75)7.00 (4.00 to 13.00)0.700
Death
    n (%)6 (3)76 (2)0.400
    time to death (d; median [IQR])19.00 (5.00 to 26.00)11.00 (3.00 to 22.25)0.400
  • a IQR, interquartile range.