Table 1.

Comparison of baseline demographic, clinical, and laboratory characteristics of 111 patients without and 37 patients with cellular crescentsa

CharacteristicNoncrescentic IgANcIgAN
ValuePValueRange
n11137
Age39 ± 150.001030 ± 1115 to 68
Gender (M/F)73/380.920024/13
sCr1.33 ± 0.850.01002.08 ± 1.850.57 to 8.24
24hP0.75 ± 0.81<0.00013.04 ± 3.030.20 to 14.30
uα2m/g uCr0.41 ± 1.36<0.00019.00 ± 12.800.00 to 52.50
FEIgG0.005 ± 0.020<0.00010.058 ± 0.1200.000 to 0.511
FEα1m0.136 ± 0.2410.00500.412 ± 0.6750.000 to 2.590
No. of glomeruli in renal biopsy18 ± 9NS17 ± 76 to 63
GGS (%)15 ± 190.004021 ± 160 to 54
TID score1.8 ± 1.7<0.00013.4 ± 1.70.0 to 6.0
Cellular crescents (%)0<0.000119 ± 154 to 63
Fibrous crescents (%)0<0.00015 ± 70 to 24
High BP42%0.220054%
Follow-up (mo)50 ± 32NS60 ± 402 to 135
  • a 24hP, 24-h proteinuria; FEα1m, fractional excretion of α1-microglobulin; FEIgG, fractional excretion of IgG; GGS, global glomerular sclerosis; sCr, serum creatinine; TID score, tubulointerstitial damage score; uα2m/g uCr, urinary excretion of α2-macroglobulin expressed in mg/g urinary creatinine.